Interpersonal Psychotherapy (Weissman, et al. Manual)

Interpersonal Psychotherapy (IPT) (Weissman, et al. Manual) is designed to treat adult patients who have been diagnosed with major depression. It can be delivered on its own or in combination with medication. IPT (Weissman, et al. Manual) aims to support patients in improving interpersonal relationships or circumstances that are directly related to the current depressive episode.

As an acute treatment, IPT (Weissman, et al. Manual) is time-limited and includes three phases—initial, middle, and termination. During the initial phase, the therapist seeks to evaluate and assess the patient (including use of and need for medication), provide psychoeducation on depression, identify a focal problem area (including grief, role disputes, role transitions, or interpersonal deficits), and set a fixed length for acute treatment. During the middle phase, the therapist’s objectives are to treat the problem selected using both general IPT techniques and problem area-specific strategies. During the termination stage, the therapist and patient aims to consolidate progress made during treatment. If needed, they discuss a separate contract for maintenance treatment sessions, medication needs/adjustments, or other treatment options. The intent of maintenance treatment is to use the same treatment techniques as acute treatment but is typically less frequent and the focal problem area(s) may shift, as needed.

IPT (Weissman, et al. Manual) is rated as a supported practice because at least one study carried out in a usual care or practice setting achieved a rating of moderate or high on design and execution and demonstrated a sustained favorable effect of at least 6 months beyond the end of treatment on at least one target outcome.

Date Research Evidence Last Reviewed: Aug 2020

Sources

The program or service description, target population, and program or service delivery and implementation information was informed by the following sources: the program or service developer’s website, the program or service manual, and the studies reviewed.

This information does not necessarily represent the views of the program or service developers. For more information on how this program or service was reviewed, visit the Review Process page or download the Handbook.

Target Population

IPT (Weissman, et al. Manual) is designed to treat adult patients diagnosed with major depression.

Program or Service Delivery and Implementation

Dosage

IPT (Weissman, et al. Manual) is typically delivered once-per-week. For acute treatment, sessions typically last for 45 to 50 minutes over the course of 12 to 16 weeks. The dosage for maintenance treatment is based on individual needs, as specified in the treatment contract. It is typically less frequent than acute treatment.

Location/Delivery Setting

Recommended Locations/Delivery Settings

IPT (Weissman, et al. Manual) is typically delivered in a clinical setting.

Location/Delivery Settings Observed in the Research

Home
Mental Health Center, Treatment Center, Therapist Office

Education, Certifications and Training

Therapists who implement IPT (Weissman, et al. Manual) should have advanced health care or mental health degrees with clinical credentials (e.g., M.D., Ph.D., MSW, R.N.). They should also have at least 2 years of clinical experience in psychotherapy and have experience working with ambulatory depressed patients. It is recommended that therapists attend a workshop or course to learn about IPT (Weissman, et al. Manual) and read the manual. IPT (Weissman, et al. Manual) therapists are encouraged to have at least 2 training cases reviewed by an experienced IPT (Weissman, et al. Manual) therapist.

Program or Service Documentation

Book/Manual/Available documentation used for review

Weissman, M. M., Markowitz, J. C., & Klerman, G. L. (2018). The guide to Interpersonal Psychotherapy: Updated and expanded edition. Oxford University Press.

Available languages

IPT (Weissman, et al. Manual) materials are available in English, Turkish, French, Mandarin, and other languages.

For More Information

Website: https://interpersonalpsychotherapy.org/

Phone: (615) 324-2365

Email: info@interpersonalpsychotherapy.org

Note: The details on Dosage; Location; Education, Certifications, and Training; Other Supporting Materials; and For More Information sections above are provided to website users for informational purposes only. This information is not exhaustive and may be subject to change.

Extent of Evidence

Results of Search and Review	Number of Studies Identified and Reviewed for Interpersonal Psychotherapy (Weissman, et al. Manual)
Identified in Search	64
Eligible for Review	8
Rated High	0
Rated Moderate	3
Rated Low	5
Reviewed Only for Risk of Harm	0

Summary of Findings

Outcome	Effect Size and Implied Percentile Effect	N of Studies (Findings)	N of Participants	Summary of Findings
Child well-being: Behavioral and emotional functioning	0.14 5	2 (4)	142	Favorable: 0 No Effect: 4 Unfavorable: 0
Adult well-being: Positive parenting practices	0.04 1	1 (2)	26	Favorable: 0 No Effect: 2 Unfavorable: 0
Adult well-being: Parent/caregiver mental or emotional health	0.58 21	3 (18)	251	Favorable: 14 No Effect: 4 Unfavorable: 0
Adult well-being: Family functioning	0.90 31	1 (1)	26	Favorable: 1 No Effect: 0 Unfavorable: 0

Note: For the effect sizes and implied percentile effects reported in the table, a positive number favors the intervention group and a negative number favors the comparison group.

Individual Study Findings

Outcome	Effect Size and Implied Percentile Effect	N of Studies (Findings)	N of Participants	Summary of Findings	Months after treatment when outcome measured
Child well-being: Behavioral and emotional functioning	0.14 5	2 (4)	142	Favorable: 0 No Effect: 4 Unfavorable: 0	-
Study 10814 - Interpersonal Psychotherapy vs. Waiting List Control (Clark, 2003)
Parent–Child Early Relational Assessment: Infant Positive Affect, Communicative and Social Skills	0.15 5	-	26	-	0
Parent–Child Early Relational Assessment: Infant Quality of Play, Interest, and Attentional Skills	0.05 1	-	26	-	0
Parent–Child Early Relational Assessment: Infant Dysregulation and Irritability	0.46 17	-	26	-	0
Study 10813 - Interpersonal Psychotherapy vs. Enhanced Community Standard (Handley, 2017)
Toddler Behavior Assessment Questionnaire: Activity Level	0.11 4	-	116	-	8
Adult well-being: Positive parenting practices	0.04 1	1 (2)	26	Favorable: 0 No Effect: 2 Unfavorable: 0	-
Study 10814 - Interpersonal Psychotherapy vs. Waiting List Control (Clark, 2003)
Parent–Child Early Relational Assessment: Maternal Negative Affect and Behavior	-0.60 -22	-	26	-	0
Parent–Child Early Relational Assessment: Maternal Intrusiveness, Insensitivity, and Inconsistency	0.67 24	-	26	-	0
Adult well-being: Parent/caregiver mental or emotional health	0.58 21	3 (18)	251	Favorable: 14 No Effect: 4 Unfavorable: 0	-
Study 10814 - Interpersonal Psychotherapy vs. Waiting List Control (Clark, 2003)
Beck Depression Inventory	0.63 23	-	26	-	0
Study 10813 - Interpersonal Psychotherapy vs. Enhanced Community Standard (Handley, 2017)
Beck Depression Inventory II	0.30 11	-	125	-	0
Study 10822 - Interpersonal Psychotherapy vs. Waiting List Control (O'Hara, 2000)
Hamilton Rating Scale for Depression-17 (4 week interim)	0.48 * 18	-	99	-	0
Hamilton Rating Scale for Depression-17 (8 week interim)	0.48 * 18	-	99	-	0
Hamilton Rating Scale for Depression-17 (end of treatment)	1.11 * 36	-	99	-	0
Beck Depression Inventory (interim week 4)	0.57 * 21	-	99	-	0
Beck Depression Inventory (interim week 8)	0.75 * 27	-	99	-	0
Beck Depression Inventory (end of treatment)	1.17 * 37	-	99	-	0
Social Adjustment Scale (interim week 4)	0.44 * 16	-	99	-	0
Social Adjustment Scale (interim week 8)	0.70 * 25	-	99	-	0
Social Adjustment Scale (end of treatment)	0.92 * 32	-	99	-	0
Postpartum Adjustment Questionnaire (interim week 4)	0.35 13	-	99	-	0
Postpartum Adjustment Questionnaire (interim week 8)	0.68 * 25	-	99	-	0
Postpartum Adjustment Questionnaire (end of treatment)	0.85 * 30	-	99	-	0
Study 10813 - Interpersonal Psychotherapy vs. Enhanced Community Standard (Toth, 2013)
Beck Depression Inventory II	0.46 * 17	-	126	-	8
Revised Hamilton Rating Scale for Depression	0.32 12	-	117	-	0
Perceived Stress Scale	0.53 * 20	-	115	-	0
Perceived Stress Scale	0.52 * 19	-	121	-	8
Adult well-being: Family functioning	0.90 31	1 (1)	26	Favorable: 1 No Effect: 0 Unfavorable: 0	-
Study 10814 - Interpersonal Psychotherapy vs. Waiting List Control (Clark, 2003)
Parent–Child Early Relational Assessment: Dyadic Disorganization and Tension	0.90 * 31	-	26	-	0

*p <.05

Note: For the effect sizes and implied percentile effects reported in the table, a positive number favors the intervention group and a negative number favors the comparison group. Effect sizes and implied percentile effects were calculated by the Prevention Services Clearinghouse as described in the Handbook of Standards and Procedures, Section 5.10.4 and may not align with effect sizes reported in individual publications.

Only publications with eligible contrasts that met design and execution standards are included in the individual study findings table.

Full citations for the studies shown in the table are available in the "Studies Reviewed" section.

Studies Reviewed

Sometimes study results are reported in more than one document, or a single document reports results from multiple studies. Studies are identified below by their Prevention Services Clearinghouse study identification numbers. To receive a rating of supported or well-supported, the favorable evidence for a program or service must have been obtained from research conducted in a usual care or practice setting.

Studies Rated Moderate

Study 10814

Clark, R., Tluczek, A., & Wenzel, A. (2003). Psychotherapy for postpartum depression: A preliminary report. American Journal of Orthopsychiatry, 73(4), 441-454. https://doi.org/10.1037/0002-9432.73.4.441

Study 10813

Toth, S. L., Rogosch, F. A., Oshri, A., Gravener-Davis, J., Sturm, R., & Morgan-Lopez, A. A. (2013). The efficacy of Interpersonal Psychotherapy for depression among economically disadvantaged mothers. Development and Psychopathology, 25(4), 1065-1078. https://doi.org/10.1017/S0954579413000370

Cicchetti, D., Toth, S. L., & Handley, E. D. (2015). Genetic moderation of Interpersonal Psychotherapy efficacy for low-income mothers with major depressive disorder: Implications for differential susceptibility. Development and Psychopathology, 27(1), 19-35. https://doi.org/10.1017/S0954579414001278

Handley, E. D., Michl-Petzing, L. C., Rogosch, F. A., Cicchetti, D., & Toth, S. L. (2017). Developmental cascade effects of Interpersonal Psychotherapy for depressed mothers: Longitudinal associations with toddler attachment, temperament, and maternal parenting efficacy. Development and Psychopathology, 29(2), 601-615. https://doi.org/10.1017/S0954579417000219

Study 10822

O'Hara, M. W, Stuart, S., Gorman, L. L., & Wenzel, A. (2000). Efficacy of Interpersonal Psychotherapy for postpartum depression. Archives of General Psychiatry, 57(11), 1039-1045. https://doi.org/10.1001/archpsyc.57.11.1039

Forman, D. R., O'Hara, M. W., Stuart, S., Gorman, L. L., Larsen, K. E., & Coy, K. C. (2007). Effective treatment for postpartum depression is not sufficient to improve the developing mother-child relationship. Development and Psychopathology, 19(2), 585-602. https://doi.org/10.1017/S0954579407070289

Nylen, K. J., O'Hara, M. W., Brock, R., Moel, J., Gorman, L., & Stuart, S. (2010). Predictors of the longitudinal course of postpartum depression following interpersonal psychotherapy. Journal of Consulting and Clinical Psychology, 78(5), 757-763. https://doi.org/10.1037/a0020623

Studies Rated Low

Study 10835

Karlsson, H., Sateri, U., & Markowitz, J. C. (2011). Interpersonal Psychotherapy for Finnish community patients with moderate to severe major depression and comorbidities: A pilot feasibility study. Nordic Journal of Psychiatry, 65(6), 427-432. https://doi.org/10.3109/08039488.2011.567421

This study received a low rating because it did not meet design confound standards.
Study 10849

Saloheimo, H. P., Markowitz, J., Saloheimo, T. H., Laitinen, J. J., Sundell, J., Huttunen, M. O., Aro, T. A., Mikkonen, T. N., Katila, H. O. (2016). Psychotherapy effectiveness for major depression: A randomized trial in a Finnish community. BMC Psychiatry, 16, 131. https://doi.org/10.1186/s12888-016-0838-1

This study received a low rating because the standards for addressing missing data were not met.
Study 10889

Power, M. J., & Freeman, C. (2012). A randomized controlled trial of IPT versus CBT in primary care: With some cautionary notes about handling missing values in clinical trials. Clinical Psychology & Psychotherapy, 19(2), 159-169. https://doi.org/10.1002/cpp.1781

This study received a low rating because baseline equivalence of the intervention and comparison groups was necessary and not demonstrated.
Study 10851

Souza, L. H., Salum, G. A., Mosqueiro, B. P., Caldieraro, M. A., Guerra, T. A., & Fleck, M. P. (2016). Interpersonal Psychotherapy as add-on for treatment-resistant depression: A pragmatic randomized controlled trial. Journal of Affective Disorders, 193, 373-380. https://doi.org/10.1016/j.jad.2016.01.004

This study received a low rating because the standards for addressing missing data were not met.
Study 10808

Brown, C., Schulberg, H. C., Madonia, M. J., Shear, M. K., & Houck, P. R. (1996). Treatment outcomes for primary care patients with major depression and lifetime anxiety disorders. The American Journal of Psychiatry, 153(10), 1293-1300. https://doi.org/10.1176/ajp.153.10.1293

Schulberg, H. C., Block, M. R., Madonia, M. J., Scott, C. P., Rodriguez, E., Imber, S. D., Perel, J., Lave, J., Houck, P. R., & Coulehan, J. L. (1996). Treating major depression in primary care practice. Eight-month clinical outcomes. Archives of General Psychiatry, 53(10), 913-919. https://doi.org/10.1001/archpsyc.1996.01830100061008

Coulehan, J. L., Schulberg, H. C., Block, M. R., Madonia, M. J., & Rodriguez, E. (1997). Treating depressed primary care patients improves their physical, mental, and social functioning. Archives Of Internal Medicine, 157(10), 1113-1120. https://doi.org/10.1001/archinte.1997.00440310079008

Lave, J. R., Frank, R. G., Schulberg, H. C., & Kamlet, M. S. (1998). Cost-effectiveness of treatments for major depression in primary care practice. Archives of General Psychiatry, 55(7), 645-651. https://doi.org/10.1001/archpsyc.55.7.645

Schulberg, H. C., Pilkonis, P. A., & Houck, P. (1998). The severity of major depression and choice of treatment in primary care practice. Journal of Consulting and Clinical Psychology, 66(6), 932-938. https://doi.org/10.1037/0022-006X.66.6.932

Brown, C., Schulberg, H. C., Sacco, D., Perel, J. M., & Houck, P. R. (1999). Effectiveness of treatments for major depression in primary medical care practice: A post hoc analysis of outcomes for African American and white patients. Journal of Affective Disorders, 53(2), 185-192. https://doi.org/10.1016/S0165-0327(98)00120-7

Brown, C., Schulberg, H. C., & Prigerson, H. G. (2000). Factors associated with symptomatic improvement and recovery from major depression in primary care patients. General Hospital Psychiatry, 22(4), 242-250. https://doi.org/10.1016/S0163-8343(00)00086-4

This study received a low rating because baseline equivalence of the intervention and comparison groups was necessary and not demonstrated.

Studies Not Eligible for Review

Study 10798

Elkin, I., Shea, T., Watkins, J. T., Imber, S. D., Sotsky, S. M., Collins, J. F., Glass, D. R., Pilkonis, P. A., Leber, W. R., Docherty, J. P., Fiester, S. J., & Parloff, M. B. (1989). National Institute of Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments. Archives of General Psychiatry, 46, 971-982. https://doi.org/10.1001/archpsyc.1989.01810110013002

Imber, S. D., Pilkonis, P. A., Sotsky, S. M., Elkin, I., Watkins, J. T., Collins, J. F., Shea, M. T., Leber, W. R., & Glass, D. R. (1990). Mode-specific effects among three treatments for depression. Journal of Consulting and Clinical Psychology, 58(3), 352-359. https://doi.org/10.1037/0022-006X.58.3.352

Sotsky, S. M., Glass, D. R., Shea, M. T., Pilkonis, P. A., Collins, J. F., Elkin, I., Watkins, J. T., Imber, S. D., Leber, W. R., Moyer, J. (1991). Patient predictors of response to psychotherapy and pharmacotherapy: Findings in the NIMH Treatment of Depression Collaborative Research Program. The American Journal of Psychiatry, 148(8), 997-1008. https://doi.org/10.1176/ajp.148.8.997

Watkins, J. T., Leber, W. R., Imber, S. D., Collins, J. F., Elkin, I., Pilkonis, P. A., Sotsky, S. M., Shea, M. T., & Glass, D. R. (1993). Temporal course of change of depression. Journal of Consulting and Clinical Psychology, 61(5), 858–864. https://doi.org/10.1037/0022-006X.61.5.858

Elkin, I., Gibbons, R. D., Shea, M. T., Sotsky, S. M., Watkins, J. T., Pilkonis, P. A., & Hedeker, D. (1995). Initial severity and differential treatment outcome in the National Institute of Mental Health Treatment of Depression Collaborative Research Program. Journal of Consulting and Clinical Psychology, 63(5), 841–847. https://doi.org/10.1037/0022-006X.63.5.841

Barber, J. P., & Muenz, L. R. (1996). The role of avoidance and obsessiveness in matching patients to cognitive and interpersonal psychotherapy: Empirical findings from the Treatment for Depression Collaborative Research Program. Journal of Consulting and Clinical Psychology, 64(5), 951–958. https://doi.org/10.1037/0022-006X.64.5.951

Agosti, V., & Ocepek-Welikson, K. (1997). The efficacy of imipramine and psychotherapy in early-onset chronic depression: A reanalysis of the National Institute of Mental Health Treatment of Depression Collaborative Research Program. Journal of Affective Disorders, 43(3), 181-186. https://doi.org/10.1016/S0165-0327(97)01428-6

Stewart, J. W., Garfinkel, R., Nunes, E. V., Donovan, S., & Klein, D. F. (1998). Atypical features and treatment response in the National Institute of Mental Health Treatment of Depression Collaborative Research Program. Journal of Clinical Psychopharmacology, 18(6), 429-434. https://doi.org/10.1097/00004714-199812000-00002

Sotsky, S. M., & Simmens, S. J. (1999). Pharmacotherapy response and diagnostic validity in atypical depression. Journal of Affective Disorders, 54(3), 237-247. https://doi.org/10.1016/S0165-0327(99)00014-2

Whisman, M. A. (2001). Marital adjustment and outcome following treatments for depression. Journal of Consulting and Clinical Psychology, 69(1), 125-129. https://doi.org/10.1037/0022-006X.69.1.125

Falconnier, L. (2009). Socioeconomic status in the treatment of depression. American Journal of Orthopsychiatry, 79(2), 148-158. https://doi.org/10.1037/a0015469

Stewart, J. G., & Harkness, K. L. (2012). Symptom specificity in the acute treatment of Major Depressive Disorder: A re-analysis of the treatment of depression collaborative research program. Journal of Affective Disorders, 137(1-3), 87-97. https://doi.org/10.1016/j.jad.2011.12.015

Blatt, S., Zuroff, D., Bondi, C., & Sanislow, C. (2000). Short- and long-term effects of medication and psychotherapy in the brief treatment of depression: Further analyses of data from the NIMH TDCRP. Psychotherapy Research, 10(2), 215-234. https://doi.org/ 10.1080/713663676

This study is ineligible for review because the publication date is prior to 1990 (Study Eligibility Criterion 4.1.1).

Study 10799

Reynolds, C. F., III, Dew, M. A., Pollock, B. G., Mulsant, B. H., Frank, E., Miller, M. D., Houck, P. R., Mazumdar, S., Butters, M. A., Stack, J. A., Schlernitzauer, M. A., Whyte, E. M., Gildengers, A., Karp, J., Lenze, E., Szanto, K., Bensasi, S., & Kupfer, D. J. (2006). Maintenance treatment of major depression in old age. The New England Journal of Medicine, 354(11), 1130-1138. https://doi.org/10.1056/NEJMoa052619

Dombrovski, A. Y., Lenze, E. J., Dew, M. A., Mulsant, B. H., Pollock, B. G., Houck, P. R., & Reynolds, C. F., III. (2007). Maintenance treatment for old-age depression preserves health-related quality of life: A randomized, controlled trial of paroxetine and interpersonal psychotherapy. Journal of the American Geriatrics Society, 55(9), 1325-1332. https://doi.org/10.1111/j.1532-5415.2007.01292.x

Dombrovski, A. Y., Mulsant, B. H., Houck, P. R., Mazumdar, S., Lenze, E. J., Andreescu, C., Cyranowski, J. M., & Reynolds, C. F., III. (2007). Residual symptoms and recurrence during maintenance treatment of late-life depression. Journal of Affective Disorders, 103(1-3), 77-82. https://doi.org/10.1016/j.jad.2007.01.020

Dew, M. A., Whyte, E. M., Lenze, E. J., Houck, P. R., Mulsant, B. H., Pollock, B. G., Stack, J. A., Bensasi, S., & Reynolds, C. F., III. (2007). Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. The American Journal of Psychiatry, 164(6), 892-899. https://doi.org/10.1176/appi.ajp.164.6.892

Andreescu, C., Lenze, E. J., Dew, M. A., Begley, A. E., Mulsant, B. H., Dombrovski, A. Y., Pollock, B. G., Stack, J., Miller, M. D., & Reynolds, C. F. (2007). Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: Controlled study. The British Journal of Psychiatry, 190(4), 344-349. https://doi.org/10.1192/bjp.bp.106.027169

Carreira, K., Miller, M. D., Frank, E., Houck, P. R., Morse, J. Q., Dew, M. A., Butters, M. A., & Reynolds, C. F., III. (2008). A controlled evaluation of monthly maintenance interpersonal psychotherapy in late-life depression with varying levels of cognitive function. International Journal of Geriatric Psychiatry, 23(11), 1110-1113. https://doi.org/10.1002/gps.2031

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10800

Beeber, L. S., Schwartz, T. A., Holditch-Davis, D., Canuso, R., Lewis, V., & Hall, H. W. (2013). Parenting enhancement, interpersonal psychotherapy to reduce depression in low-income mothers of infants and toddlers: A randomized trial. Nursing Research, 62(2), 82-90. https://doi.org/10.1097/NNR.0b013e31828324c2

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10801

Bellino, S., Zizza, M., Rinaldi, C., & Bogetto, F. (2006). Combined treatment of major depression in patients with borderline personality disorder: a comparison with pharmacotherapy. Canadian Journal Of Psychiatry, 51(7), 453-460. https://doi.org/10.1177/070674370605100707

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10802

Benvenuti, A., Rucci, P., Miniati, M., Papasogli, A., Fagiolini, A., Cassano, G. B., Swartz, H., & Frank, E. (2008). Treatment-emergent mania/hypomania in unipolar patients. Bipolar Disorders, 10(6), 726-732. https://doi.org/10.1111/j.1399-5618.2008.00613.x

Miniati, M., Rucci, P., Frank, E., Oppo, A., Kupfer, D. J., Fagiolini, A., & Cassano, G. B. (2009). Sensitivity to change and predictive validity of the MOODS-SR questionnaire, last-month version. Psychotherapy and Psychosomatics, 78(2), 116-124. https://doi.org/10.1159/000201937

Frank, E., Cassano, G. B., Rucci, P., Thompson, W. K., Kraemer, H. C., Fagiolini, A., Maggi, L., Kupfer, D. J., Shear, M. K., Houck, P. R., Calugi, S., Grochocinski, V. J., Scocco, P., Buttenfield, J., & Forgione, R. N. (2011). Predictors and moderators of time to remission of major depression with interpersonal psychotherapy and SSRI pharmacotherapy. Psychological Medicine, 41(1), 151-162. https://doi.org/10.1017/S0033291710000553

Rucci, P., Frank, E., Calugi, S., Miniati, M., Benvenuti, A., Wallace, M., Fagiolini, A., Maggi, L., Kupfer, D. J., & Cassano, G. B. (2011). Incidence and predictors of relapse during continuation treatment of major depression with SSRI, interpersonal psychotherapy, or their combination. Depression and Anxiety, 28(11), 955-962. https://doi.org/10.1002/da.20894

Rucci, P., Frank, E., Scocco, P., Calugi, S., Miniati, M., Fagiolini, A., & Cassano, G. B. (2011). Treatment-emergent suicidal ideation during 4 months of acute management of unipolar major depression with SSRI pharmacotherapy or interpersonal psychotherapy in a randomized clinical trial. Depression and Anxiety, 28(4), 303-309. https://doi.org/10.1002/da.20758

Frank, E., Kupfer, D. J., Rucci, P., Lotz-Wallace, M., Levenson, J., Fournier, J., & Kraemer, H. C. (2012). Simultaneous evaluation of the harms and benefits of treatments in randomized clinical trials: Demonstration of a new approach. Psychological Medicine, 42(4), 865-873. https://doi.org/10.1017/S0033291711001619

Levenson, J. C., Wallace, M. L., Fournier, J. C., Rucci, P., & Frank, E. (2012). The role of personality pathology in depression treatment outcome with psychotherapy and pharmacotherapy. Journal of Consulting and Clinical Psychology, 80(5), 719-729. https://doi.org/10.1037/a0029396

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10803

Bernecker, S. L., Constantino, M. J., Atkinson, L. R., Bagby, R. M., Ravitz, P., & McBride, C. (2016). Attachment style as a moderating influence on the efficacy of cognitive-behavioral and interpersonal psychotherapy for depression: A failure to replicate. Psychotherapy, 53(1), 22-33. https://doi.org/10.1037/pst0000036

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10804

Blanco, C., Markowitz, J. C., Hellerstein, D. J., Nezu, A. M., Wall, M., Olfson, M., Chen, Y., Levenson, J., Onishi, M., Varona, C., Okuda, M., & Hershman, D. L. (2019). A randomized trial of interpersonal psychotherapy, problem solving therapy, and supportive therapy for major depressive disorder in women with breast cancer. Breast Cancer Research And Treatment, 173(2), 353-364. https://doi.org/10.1007/s10549-018-4994-5

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10805

Blom, M. B. J., Jonker, K., Dusseldorp, E., Spinhoven, P., Hoencamp, E., Haffmans, J., & van Dyck, R. (2007). Combination treatment for acute depression is superior only when psychotherapy is added to medication. Psychotherapy and Psychosomatics, 76(5), 289-297. https://doi.org/10.1159/000104705

Blom, M. B. J., Spinhoven, P., Hoffman, T., Jonker, K., Hoencamp, E., Haffmans, P. M. J., & van Dyck, R. (2007). Severity and duration of depression, not personality factors, predict short term outcome in the treatment of major depression. Journal of Affective Disorders, 104(1-3), 119-126. https://doi.org/10.1016/j.jad.2007.03.010

Blom, M. B. J., Hoek, H. W., Spinhoven, P., Hoencamp, E., Haffmans, P. M. J., & van Dyck, R. (2010). Treatment of depression in patients from ethnic minority groups in the Netherlands. Transcultural Psychiatry, 47(3), 473-490. https://doi.org/10.1177/1363461510374561

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10806

van Schaik, A., van Marwijk, H., Adèr, H., van Dyck, R., de Haan, M., Penninx, B., van der Kooij, K., van Hout, H., & Beekman, A. (2006). Interpersonal Psychotherapy for Elderly Patients in Primary Care. The American Journal of Geriatric Psychiatry, 14(9), 777-786. https://doi.org/10.1097/01.JGP.0000199341.25431.4b

Bosmans, J. E., va Schaik, D. J. F., Heymans, M. W., van Marwijk, H. W. J., van Hout, H. P. J., & de Bruijne, M. C. (2007). Cost-effectiveness of interpersonal psychotherapy for elderly primary care patients with major depression. International Journal Of Technology Assessment In Health Care, 23(4), 480-487. https://doi.org/10.1017/S0266462307070572

van Schaik, D. J. F., van Marwijk, H. W. J., Beekman, A. T. F., de Haan, M., & van Dyck, R. (2007). Interpersonal psychotherapy (IPT) for late-life depression in general practice: uptake and satisfaction by patients, therapists and physicians. BMC Family Practice, 8, 52-52. https://doi.org/10.1186/1471-2296-8-52

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10807

Brody, A. L., Saxena, S., Stoessel, P., Gillies, L. A., Fairbanks, L. A., Alborzian, S., Phelps, M. E., Huang, S. -C., Wu, H. -M., Ho, M. L., Ho, M. K., Au, S. C., Maidment, K., & Baxter, L. R., Jr. (2001). Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: Preliminary findings. Archives of General Psychiatry, 58(7), 631-640. https://doi.org/10.1001/archpsyc.58.7.631

Brody, A. L., Saxena, S., Mandelkern, M. A., Fairbanks, L. A., Ho, M. L., & Baxter, L. R., Jr. (2001). Brain metabolic changes associated with symptom factor improvement in major depressive disorder. Biological Psychiatry, 50(3), 171-178. https://doi.org/10.1016/S0006-3223(01)01117-9

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10809

Bulmash, E. L., Harkness, K. L., Stewart, J. G., & Bagby, R. M. (2009). Personality, stressful life events, and treatment response in major depression. Journal of Consulting and Clinical Psychology, 77(6), 1067-1077. https://doi.org/10.1037/a0017149

Harkness, K. L., Bagby, R. M., & Kennedy, S. H. (2012). Childhood maltreatment and differential treatment response and recurrence in adult major depressive disorder. Journal of Consulting and Clinical Psychology, 80(3), 342-353. https://doi.org/10.1037/a0027665

McBride, C. A., Leslie; Quilty, Lena C.; Bagby, R. Michael. (2006). Attachment as moderator of treatment outcome in major depression: A randomized control trial of interpersonal psychotherapy versus cognitive behavior therapy. Journal of Consulting and Clinical Psychology, 74(6), 1041-1054. https://doi.org/10.1037/0022-006X.74.6.1041

Marshall, M. B., Zuroff, D. C., McBride, C., & Bagby, R. M. (2008). Self-criticism predicts differential response to major depression. Journal of Clinical Psychology, 64, 231-244. https://doi.org/10.1002/jclp.20438

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10810

Buttorff, C., Hock, R. S., Weiss, H. A., Smita, N., Araya, R., Kirkwood, B. R., Chisholm, D., & Patel, V. (2012). Economic evaluation of a task-shifting intervention for common mental disorders in India. Bulletin of the World Health Organization, 90(11), 813-821. https://doi.org/10.2471/BLT.12.104133

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10811

Reynolds, C. F. (1997). Treatment of major depression in later life: A life cycle perspective. Psychiatric Quarterly, 68(3), 221-246. https://doi.org/10.1023/A:1025484123244

Reynolds, C. F., Frank, E., Perel, J. M., Imber, S. D., Cornes, C., Morycz, R. K., Mazumdar, S., Miller, M. D., Pollock, B. G., Rifai, A. H., Stack, J. A., George, C. J., Houck, P. R., & Kupfer, D. J. (1992). Combined pharmacotherapy and psychotherapy in the acute and continuation treatment of elderly patients with recurrent major depression: A preliminary report. The American Journal of Psychiatry, 149(12), 1687-1692. https://doi.org/10.1176/ajp.149.12.1687

Buysse, D. J., Reynolds, C. F., III, Hoch, C. C., Houck, P. R., Kupfer, D. J., Mazumdar, S., & Frank, E. (1996). Longitudinal effects of nortriptyline on EEG sleep and the likelihood of recurrence in elderly depressed patients. Neuropsychopharmacology, 14(4), 243-252. https://doi.org/10.1016/0893-133X(95)00114-S

Pasternak, R. E., Prigerson, H., Hall, M., Miller, M. D., Fasiczka, A., Mazumdar, S., & Reynolds, C. P. (1997). The posttreatment illness course of depression in bereaved elders: High relapse/recurrence rates. The American Journal of Geriatric Psychiatry, 5(1), 54-59. https://doi.org/10.1097/00019442-199705010-00007

Reynolds, C. F., III, Dew, M. A., Frank, E., Begley, A. E., Miller, M. D., Cornes, C., Mazumdar, S., Perel, J. M., & Kupfer, D. J. (1998). Effects of age at onset of first lifetime episode of recurrent major depression on treatment response and illness course in elderly patients. The American Journal of Psychiatry, 155(6), 795-799. https://doi.org/ 10.1176/ajp.155.6.795

Reynolds, C. F., III; Frank, E., Dew, M. A., Houck, P. R., Miller, M., Mazumdar, S., Perel, J. M., & Kupfer, D. J. (1999). Treatment of 70+-year-olds with recurrent major depression: Excellent short-term but brittle long-term response. The American Journal of Geriatric Psychiatry, 7(1), 64-69. https://doi.org/10.1097/00019442-199924710-00009

Reynolds, C. F., III; Frank, E., Perel, J. M., Imber, S. D., Cornes, C., Miller, M. D., Mazumdar, S., Houck, P. R., Dew, M. A., Stack, J. A., Pollock, B. G., & Kupfer, D. J. (1999). Nortriptyline and Interpersonal Psychotherapy as maintenance therapies for recurrent major depression: A randomized controlled trial in patients older than 59 years. JAMA, 281(1), 39-45. https://doi.org/10.1001/jama.281.1.39

Reynolds, C. F., III, Frank, E., Perel, J. M., Imber, S. D., Cornes, C., Miller, M. D., Mazumdar, S., Houck, P. R., Dew, M. A., Stack, J. A., Pollock, B. G., & Kupfer, D. J. (1999). 'Nortriptyline and Interpersonal Psychotherapy as maintenance therapies for recurrent major depression: A randomized controlled trial in patients older than 59 years': Reply. JAMA, 281(20), 1891-1892.

Dew, M. A., Reynolds, C. F., III, Mulsant, B., Frank, E., Houck, P. R., Mazumdar, S., Begley, A., & Kupfer, D. J. (2001). Initial recovery patterns may predict which maintenance therapies for depression will keep older adults well. Journal of Affective Disorders, 65(2), 155-166. https://doi.org/10.1016/S0165-0327(00)00280-9

Lenze, E. J., Dew, M. A., Mazumdar, S., Begley, A. E., Cornes, C., Miller, M. D., Imber, S. D., Frank, E., Kupfer, D. J., & Reynolds, C. F., III. (2002). Combined pharmacotherapy and psychotherapy as maintenance treatment for late-life depression: Effects on social adjustment. The American Journal of Psychiatry, 159(3), 466-468. https://doi.org/10.1176/appi.ajp.159.3.466

Martire, L. M., Shulz, R., Reynolds, C. F., III, Karp, J. F., Gildengers, A. G., & Whyte, E. M. (2010). Treatment of late-life depression alleviates caregiver burden. Journal of the American Geriatrics Society, 58(1), 23-29. https://doi.org/10.1111/j.1532-5415.2009.02610.x

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10816

Cyranowski, J. M., Swartz, H. A., Hofkens, T. L., & Frank, E. (2009). Emotional and cardiovascular reactivity to a child-focused interpersonal stressor among depressed mothers of psychiatrically ill children. Depression and Anxiety, 26(2), 110-116. https://doi.org/10.1002/da.20515

Swartz, H. A., Frank, E., Zuckoff, A., Cyranowski, J. M., Houck, P. R., Cheng, Y., Fleming, D., Grote, N. K., Brent, D. A., & Shear, M. K. (2008). Brief Interpersonal Psychotherapy for depressed mothers whose children are receiving psychiatric treatment. American Journal of Psychiatry, 165(9), 1155-1162. https://doi.org/10.1176/appi.ajp.2008.07081339

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10817

Davis, E. P., Hankin, B. L., Swales, D. A., & Hoffman, M. C. (2018). An experimental test of the fetal programming hypothesis: Can we reduce child ontogenetic vulnerability to psychopathology by decreasing maternal depression? Development and Psychopathology, 30(3), 787-806. https://doi.org/10.1017/S0954579418000470

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10818

Duberstein, P. R., Ward, E. A., Chaudron, L. H., He, H., Toth, S. L., Wang, W., Van Orden, K, A., Gamble, S. A., & Talbot, N. L. (2018). Effectiveness of interpersonal psychotherapy-trauma for depressed women with childhood abuse histories. Journal of Consulting and Clinical Psychology, 86(10), 868-878. https://doi.org/10.1037/ccp0000335

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10819

Ekeblad, A., Falkenström, F., Andersson, G., Vestberg, R., & Holmqvist, R. (2016). Randomized trial of Interpersonal Psychotherapy and Cognitive Behavioral Therapy for Major Depressive Disorder in a community-based psychiatric outpatient clinic. Depression and Anxiety, 33(12), 1090-1098. https://doi.org/10.1002/da.22495

Ekeblad, A., Falkenström, F., & Holmqvist, R. (2016). Reflective functioning as predictor of working alliance and outcome in the treatment of depression. Journal of Consulting and Clinical Psychology, 84(1), 67-78. https://doi.org/10.1037/ccp0000055

Falkenström, F., Ekeblad, A., Holmqvist, R. (2016). Improvement of the working alliance in one treatment session predicts improvement of depressive symptoms by the next session. Journal of Consulting and Clinical Psychology, 84(8), 738-751. https://doi.org/10.1037/ccp0000119

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10821

Johnson, J. E., Miller, T. R., Stout, R. L., Zlotnick, C., Cerbo, L. A., Andrade, J. T., & Wiltsey-Stirman, S. (2016). Study protocol: Hybrid Type I cost-effectiveness and implementation study of Interpersonal Psychotherapy (IPT) for men and women prisoners with major depression. Contemporary Clinical Trials, 47, 266-274. https://doi.org/10.1016/j.cct.2016.01.013

Felton, J. W.. Hailemariam, M., Richie, F., Reddy, M. K., Edukere, S., Zlotnick, C., & Johnson, J. E. (2020). Preliminary efficacy and mediators of interpersonal psychotherapy for reducing posttraumatic stress symptoms in an incarcerated population. Psychotherapy Research, 30(2), 239-250. https://doi.org/10.1080/10503307.2019.1587192

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10823

Frank, E., Kupfer, D. J., Perel, J. M., Cornes, C., Jarrett, D. B., Mallinger, A. G., Thase, M. E., McEachran, A. B., & Grochocinski, V. J. (1990). Three-year outcomes for maintenance therapies in recurrent depression. Archives of General Psychiatry, 47(12), 1093-1099.

Karp, J. F., Buysse, D. J., Houck, P. R., Cherry, C., Kupfer, D. J., & Frank, E. (2004). Relationship of variability in residual symptoms with recurrence of major depressive disorder during maintenance treatment. The American Journal of Psychiatry, 161(10), 1877-1884. https://doi.org/10.1176/appi.ajp.161.10.1877

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10824

Frank, E., Grochocinski, V. J., Spanier, C. A., Buysse, D. J., Cherry, C. R., Houck, P. R., Stapf, D. M., & Kupfer, D. J. (2000). Interpersonal Psychotherapy and antidepressant medication: Evaluation of a sequential treatment strategy in women with recurrent major depression. The Journal of Clinical Psychiatry, 61(1), 51-57. https://doi.org/10.4088/JCP.v61n0112

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10825

Frank, E., Kupfer, D. J., Buysse, D. J., Swartz, H. A., Pilkonis, P. A., Houck, P. R., Rucci, P., Novick, D. M., Grochocinski, V. J., Stapf, D. M. (2007). Randomized trial of weekly, twice-monthly, and monthly Interpersonal Psychotherapy as maintenance treatment for women with recurrent depression. The American Journal of Psychiatry, 164(5), 761-767. https://doi.org/10.1176/appi.ajp.164.5.761

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10826

Frasure-Smith, N., Koszycki, D., Swenson, J. R., Baker, B., van Zyl, L. T., Laliberté, M. A., Abramson, B. L., Lambert, J., Gravel, G., & Lespérance, F. (2006). Design and rationale for a randomized, controlled trial of interpersonal psychotherapy and citalopram for depression in coronary artery disease (CREATE). Psychosomatic Medicine, 68(1), 87-93. https://doi.org/ 10.1097/01.psy.0000195833.68482.27

Lespérance, F., Frasure-Smith, N., Koszycki, D., Laliberté, M.-A., van Zyl, L. T., Baker, B., Swenson, J. R., Ghatavi, K., Abramson, B. L., Dorian, P., & Guertin, M.-C. (2007). Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA: Journal of the American Medical Association, 297(4), 367-379. https://doi.org/10.1001/jama.297.4.367

Lespérance, F., & Frasure-Smith. N. (2007). 'Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease': Reply. JAMA: Journal of the American Medical Association, 297(17), 1880-1880. https://doi.org/10.1001/jama.297.17.1880-a

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10827

Ghesquiere, A. R., Park, M., Bogner, H. R., Greenberg, R. L., & Bruce, M. L. (2014). The effect of recent bereavement on outcomes in a primary care depression intervention study. The American Journal of Geriatric Psychiatry, 22(12), 1555-1564. https://doi.org/10.1016/j.jagp.2013.12.005

Bruce, M. L., & Pearson, J. L. (1999). Designing an intervention to prevent suicide: PROSPECT (Prevention of Suicide in Primary Care Elderly: Collaborative Trial). Dialogues in Clinical Neuroscience, 1, 100–112.

Bruce, M. L., Ten Have, T. R., Reynolds, C. F., III., Katz, I. I., Schulberg, H. C., Mulsant, B. H., Brown, G. K., McAvay, G. J., Pearson, J. L., & Alexopoulos, G. S. (2004). Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: A randomized controlled trial. JAMA, 291(9), 1081-1091. https://doi.org/10.1001/jama.291.9.1081

Mulsant, B. H., Alexopoulos, G. S., Reynolds, C. F., III., Katz, I. R., Abrams, R., Oslin, D., Schulberg, H. C., & PROSPECT Study Group. (2001). Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. International Journal of Geriatric Psychiatry, 16(6), 585-592. https://doi.org/10.1002/gps.465

Schulberg, H. C., Post, E. P., Raue, P. J., Ten Have, T., Miller, M., & Bruce, M. L. (2007). Treating late-life depression with interpersonal psychotherapy in the primary care sector. International Journal of Geriatric Psychiatry, 22(2), 106-114. https://doi.org/10.1002/gps.1700

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10828

Gois, C., Dias, V. V., Carmo, I., Duarte, R., Ferro, A., Santos, A. L., Sousa, F., & Barbosa, A. (2014). Treatment response in type 2 diabetes patients with major depression. Clinical Psychology & Psychotherapy, 21(1), 39-48. https://doi.org/10.1002/cpp.1817

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10829

Greenlee, A., Karp, J. F., Dew, M. A., Houck, P., Andreescu, C., & Reynolds, C. F., III. (2010). Anxiety impairs depression remission in partial responders during extended treatment in late-life. Depression and Anxiety, 27(5), 451-456. https://doi.org/10.1002/da.20672

Reynolds, C. F., III, Dew, M. A., Martire, L. M., Miller, M. D., Cyranowski, J. M., Lenze, E., Whyte, E. M., Mulsant, B. H., Pollock, B. G., Karp, J. F., Gildengers, A., Szanto, K., Dombrovski, A. Y., Andreescu, C., Butters, M. A., Morse, J. Q., Houck, P. R., Bensasi, S., Mazumdar, S., Stack, J. A., & Frank, E. (2010). Treating depression to remission in older adults: A controlled evaluation of combined escitalopram with interpersonal psychotherapy versus escitalopram with depression care management. International Journal of Geriatric Psychiatry, 25(11), 1134-1141. https://doi.org/10.1002/gps.2443

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10830

Grote, N. K., Swartz, H. A., & Zuckoff, A. (2008). Enhancing Interpersonal Psychotherapy for mothers and expectant mothers on low incomes: Adaptations and additions. Journal of Contemporary Psychotherapy, 38(1), 23-33. https://doi.org/10.1007/s10879-007-9065-x

Grote, N. K., Spieker, S. J., Lohr, M. J., Geibel, S. L., Swartz, H. A., Frank, E., Houck, P. R., & Katon, W. (2012). Impact of childhood trauma on the outcomes of a perinatal depression trial. Depression and Anxiety, 29(7), 563-573. https://doi.org/10.1002/da.21929

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10831

Hajiheidari, M., Sharifi, M., & Khorvash, F. (2013). The effect of Interpersonal Psychotherapy on marriage adaptive and postpartum depression in Isfahan. International Journal of Preventive Medicine, 4(Suppl 2), S256-S261.

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10832

Luty, S. E., Carter, J. D., McKenzie, J. M., Rae, A. M., Frampton, C. M. A., Mulder, R. T., & Joyce, P. R. (2007). Randomised controlled trial of Interpersonal Psychotherapy and cognitive-behavioural therapy for depression. The British Journal of Psychiatry, 190, 496-502. https://doi.org/10.1192/bjp.bp.106.024729

Joyce, P. R., McKenzie, J. M., Carter, J. D., Rae, A. M., Luty, S. E., Frampton, C. M. A., & Mulder, R. T. (2007). Temperament, character and personality disorders as predictors of response to Interpersonal Psychotherapy and cognitive-behavioural therapy for depression. The British Journal of Psychiatry, 190, 503-508. https://doi.org/10.1192/bjp.bp.106.024737

Harley, J., Luty, S., Carter, J., Mulder, R., & Joyce, P. (2010). Elevated C-reactive protein in depression: A predictor of good long-term outcome with antidepressants and poor outcome with psychotherapy. Journal of Psychopharmacology, 24(4), 625-626. https://doi.org/10.1177/0269881109102770

Johnstone, J. M., Carter, J. D., Luty, S. E., Mulder, R. T., Frampton, C. M., & Joyce, P. R. (2013). Maternal care and paternal protection influence response to psychotherapy treatment for adult depression. Journal of Affective Disorders, 149(1-3), 221-229. https://doi.org/10.1016/j.jad.2013.01.030

Mulder, R., Boden, J., Carter, J., Luty, S., & Joyce, P. (2017). Ten month outcome of cognitive behavioural therapy v Interpersonal Psychotherapy in patients with major depression: A randomised trial of acute and maintenance psychotherapy. Psychological Medicine, 47(14), 2540-2547. https://doi.org/10.1017/S0033291717001106

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10834

Huibers, M. J., Cohen, Z. D., Lemmens, L. H., Arntz, A., Peeters, F. P., Cuijpers, P., & DeRubeis, R. J. (2015). Predicting optimal outcomes in cognitive therapy or Interpersonal Psychotherapy for depressed individuals using the personalized advantage index approach. PLoS One, 10(11):e0140771. https://doi.org/ 10.1371/journal.pone.0140771

Lemmens, L. H., DeRubeis, R. J., Arntz, A., Peeters, F. P., & Huibers, M. J. (2016). Sudden gains in cognitive therapy and interpersonal psychotherapy for adult depression. Behaviour Research and Therapy, 77, 170-176. https://doi.org/10.1016/j.brat.2015.12.014

Lemmens, L. H. J. M., Galindo-Garre, F., Arntz, A., Peeters, F., Hollon, S. D., DeRubeis, R. J., & Huibers, M. J. H. (2017). Exploring mechanisms of change in cognitive therapy and interpersonal psychotherapy for adult depression. Behaviour Research and Therapy, 94, 81-92. https://doi.org/10.1016/j.brat.2017.05.005

Lemmens, L. H. J. M., van Bronswijk, S. C., Peeters, F., Arntz, A., Hollon, S. D., & Huibers, M. J. H. (2019). Long-term outcomes of acute treatment with cognitive therapy v Interpersonal psychotherapy for adult depression: Follow-up of a randomized controlled trial. Psychological Medicine, 49(3), 465-473. https://doi.org/10.1017/S0033291718001083

van Bronswijk, S. C., Lemmens, L. H. J. M., Viechtbauer, W., Huibers, M. J. H., Arntz, A., & Peeters, F. P. M. L. (2018). The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder. Journal of Affective Disorders, 225, 530-538. https://doi.org/10.1016/j.jad.2017.08.043

van Bronswijk, S. C., Lemmens, L. H. J. M., Huibers, M. J. H., Arntz, A., & Peeters, F. P. M. L. (2018). The influence of comorbid anxiety on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder. Journal of Affective Disorders, 232, 52-60. https://doi.org/10.1016/j.jad.2018.02.003

van Bronswijk, S. C., DeRubeis, R. J., Lemmens, L. H. J. M., Peeters, F. P. M. L., Keefe, J. R., Cohen, Z. D., & Huibers, M. J. H. (2019). Precision medicine for long-term depression outcomes using the Personalized Advantage Index approach: Cognitive therapy or Interpersonal Psychotherapy? Psychological Medicine, 1-11. https://doi.org/10.1017/S0033291719003192

Lemmens, L. H. J. M., Arntz., A., Peeters, F., Hollon, S. D., Roefs, A., & Huibers, M. J. H. (2015). Clinical effectiveness of cognitive therapy v Interpersonal Psychotherapy for Depression: Results of a randomized controlled trial. Psychological Medicine, 45(10), 2095-2110. https://doi.org/10.1017/S0033291715000033

Lemmens, L. H. J. M., Arntz, A., Peeters, F. P. M. L., Hollon, S. D., Roefs, A., & Huibers, M. J. H. (2011). Effectiveness, relapse prevention and mechanisms of change of cognitive therapy vs. interpersonal therapy for depression: Study protocol for a randomised controlled trial. Trials, 12, 150. https://doi.org/10.1186/1745-6215-12-150

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10836

Koszycki, D., Bisserbe, J.-C., Blier, P., Bradwejn, J., & Markowitz, J. (2012). Interpersonal psychotherapy versus brief supportive therapy for depressed infertile women: First pilot randomized controlled trial. Archives of Women's Mental Health, 15(3), 193-201. https://doi.org/10.1007/s00737-012-0277-z

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10837

Kumpula, M. J., Wagner, H. R., Dedert, E. A., Crowe, C. M., Day, K. T., Powell, K., Batdorf, W. H., Shabana, H., Kim, E., & Kimbrel, N. A. (2019). An evaluation of the effectiveness of evidence-based psychotherapies for depression to reduce suicidal ideation among male and female veterans. Women's Health Issues, 29(Suppl 1), S103-S111. https://doi.org/10.1016/j.whi.2019.04.013

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10838

Markowitz, J. C., Klerman, G. L., Clougherty, Kathleen F.; Spielman, Lisa A.; Jacobsberg, Lawrence B.; Fishman, Baruch; Frances, Allen J.; Kocsis, James H.; Perry, Samuel W. (1995). Individual psychotherapies for depressed HIV-positive patients. The American Journal of Psychiatry, 152(10), 1504-1509. https://doi.org/10.1176/ajp.152.10.1504

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10839

Markowitz, J. C., Kocsis, J. H., Fishman, B., Spielman, L. A., Jacobsberg, L. B., Frances, A. J., Klerman, G. L., & Perry, S. W. (1998). Treatment of depressive symptoms in human immunodeficiency virus-positive patients. Archives of General Psychiatry, 55(5), 452-457. https://doi.org/10.1001/archpsyc.55.5.452

Markowitz, J. C., Spielman, L. A., Sullivan, M., & Fishman, B. (2000). An exploratory study of ethnicity and psychotherapy outcome among HIV-positive patients with depressive symptoms. Journal of Psychotherapy Practice & Research, 9(4), 226-231.

Markowitz, J. C., Spielman, L. A., Scarvalone, P. A., & Perry, S. W. (2000). Psychotherapy adherence of therapists treating HIV-positive patients with depressive symptoms. Journal of Psychotherapy Practice & Research, 9(2), 75-80.

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10840

Martin, S. D., Martin, E., Rai, S. S., Richardson, M. A., & Royall, R. (2001). Brain blood flow changes in depressed patients treated with Interpersonal Psychotherapy or venlafaxine hydrochloride: Preliminary findings. Archives of General Psychiatry, 58(7), 641-648. https://doi.org/10.1001/archpsyc.58.7.641

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10842

O'Hara, M. W., Pearlstein, T., Stuart, S., Long, J. D., Mills, J. A., & Zlotnick, C. (2019). A placebo controlled treatment trial of sertraline and Interpersonal Psychotherapy for postpartum depression. Journal of Affective Disorders, 245, 524-532. https://doi.org/10.1016/j.jad.2018.10.361

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10843

Onu, C., Ongeri, L., Bukusi, E., Cohen, C. R., Neylan, T. C., Oyaro, P., Rota, G., Otewa, F., Delucchi, K. L., & Meffert, S. M. (2016). Interpersonal Psychotherapy for depression and posttraumatic stress disorder among HIV-positive women in Kisumu, Kenya: Study protocol for a randomized controlled trial. Trials, 17, 64. https://doi.org/10.1186/s13063-016-1187-6

Onu, C., Ongeri, L., Bukusi, E., Cohen, C. R., Neylan, T. C., Oyaro, P., Rota, G., Otewa, F., Delucchi, K. L., & Meffert, S. M. (2016). Erratum to: 'Interpersonal Psychotherapy for depression and posttraumatic stress disorder among HIV-positive women in Kisumu, Kenya: Study protocol for a randomized controlled trial'. Trials, 17, 151. https://doi.org/10.1186/s13063-016-1289-1

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10844

Pearlstein, T. B., Zlotnick, C., Battle, C. L., Stuart, S., O'Hara, M. W., Price, A. B., Grause, M. A., & Howard, M. (2006). Patient choice of treatment for postpartum depression: A pilot study. Archives of Women's Mental Health, 9(6), 303-308. https://doi.org/10.1007/s00737-006-0145-9

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10845

Peeters, F., Huibers, M., Roelofs, J., van Breukelen, G., Hollon, S. D., Markowitz, J. C., van Os, J., & Arntz, A. (2013). The clinical effectiveness of evidence-based interventions for depression: A pragmatic trial in routine practice. Journal of Affective Disorders, 145(3), 349-355. https://doi.org/10.1016/j.jad.2012.08.022

Wigman, J. T., van Os, J., Abidi, L., Huibers, M. J., Roelofs, J., Arntz, A., Kelleher, I., & Peeters, F. P. (2014). Subclinical psychotic experiences and bipolar spectrum features in depression: Association with outcome of psychotherapy. Psychological Medicine, 44(2), 325-336. https://doi.org/10.1017/S0033291713000871

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10846

Quilty, L. C., Taylor, G. J., McBride, C., & Bagby, R. M. (2017). Relationships among alexithymia, therapeutic alliance, and psychotherapy outcome in major depressive disorder. Psychiatry Research, 254, 75-79. https://doi.org/10.1016/j.psychres.2017.04.047

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10847

Raue, P. J., Schulberg, H. C., Heo, M., Klimstra, S., & Bruce, M. L. (2009). Patients' depression treatment preferences and initiation, adherence, and outcome: A randomized primary care study. Psychiatric Services, 60(3), 337-343. https://doi.org/10.1176/appi.ps.60.3.337

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10848

Reynolds, C. F., III., Miller, M. D., Pasternak, R. E., Frank, E., Perel, J. M., Cornes, C., Houck, P. R., Mazumdar, S., Dew, M. A., & Kupfer, D. J. (1999). Treatment of bereavement-related major depressive episodes in later life: A controlled study of acute and continuation treatment with nortriptyline and interpersonal psychotherapy. The American Journal of Psychiatry, 156(2), 202-208. https://doi.org/10.1176/foc.2.2.260

Taylor, M. P., Reynolds, C. F., III., Frank, E., Cornes, C., Miller, M. D., Stack, J. A., Begley, A. E., Mazumdar, S., Dew, M. A., & Kupfer, D. J. (1999). Which elderly depressed patients remain well on maintenance interpersonal psychotherapy alone?: Report from the Pittsburgh study of maintenance therapies in late-life depression. Depression and Anxiety, 10(2), 55-60. https://doi.org/10.1002/(sici)1520-6394(1999)10:2<55::aid-da3>3.0.co;2-f

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10850

Schramm, E., Zobel, I., Dykierek, P., Kech, S., Brakemeier, E.-L., Külz, A., & Berger, M. (2011). Cognitive behavioral analysis system of psychotherapy versus Interpersonal Psychotherapy for early-onset chronic depression: A randomized pilot study. Journal of Affective Disorders, 129(1-3), 109-116. https://doi.org/10.1016/j.jad.2010.08.003

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10852

Spinelli, M. G., & Endicott, J. (2003). Controlled clinical trial of Interpersonal Psychotherapy versus parenting education program for depressed pregnant women. The American Journal of Psychiatry, 160(3), 555-562. https://doi.org/10.1176/appi.ajp.160.3.555

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10853

Spinelli, M. G., Endicott, J., Leon, A. C., Goetz, R. R., Kalish, R. B., Brustman, L. E., Carmona, Y. R., Meyreles, Q., Vega, M., & Schulick, J. L. (2013). A controlled clinical treatment trial of Interpersonal Psychotherapy for depressed pregnant women at 3 New York City sites. The Journal of Clinical Psychiatry, 74(4), 393-399. https://doi.org/10.4088/JCP.12m07909

Spinelli, M. G., Endicott, J., & Goetz, R. R. (2013). Increased breastfeeding rates in black women after a treatment intervention. Breastfeeding Medicine, 8(6), 479-484. https://doi.org/10.1089/bfm.2013.0051

Spinelli, M. G., Endicott, J., & Goetz, R. R. (2015). Disagreement between therapist raters and independent evaluators in a controlled clinical trial of Interpersonal Psychotherapy for depressed pregnant women. Journal of Psychiatric Practice, 21(2), 114-123. https://doi.org/10.1097/01.pra.0000462604.79606.4e

Spinelli, M. G., Endicott, J., Goetz, R. R., & Segre, L. S. (2016). Reanalysis of efficacy of Interpersonal Psychotherapy for antepartum depression versus parenting education program: initial severity of depression as a predictor of treatment outcome. The Journal of Clinical Psychiatry, 77(4), 535-540. https://doi.org/10.4088/JCP.15m09787

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10854

Strauman, T. J., Kolden, G. G., Stromquist, V., Davis, N., Kwapil, L., Heerey, E., & Schneider, K. (2001). The effects of treatments for depression on perceived failure in self-regulation. Cognitive Therapy and Research, 25(6), 693–712. https://doi.org/10.1023/A:1012915205800 This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10858

Browne, G., Steiner, M., Roberts, J., Gafni, A., Byrne, C., Dunn, E., Bell, B., Mills, M., Chalklin, L., Wallik, D., & Kraemer, J. (2002). Sertraline and/or Interpersonal Psychotherapy for patients with dysthymic disorder in primary care: 6-month comparison with longitudinal 2-year follow-up of effectiveness and costs. Journal of Affective Disorders, 68(2-3), 317-330. https://doi.org/10.1016/S0165-0327(01)00343-3

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).

Study 10863

Shear, K., Frank, E., Houck, P. R., & Reynolds, C. F., III. (2005). Treatment of complicated grief: A randomized controlled trial. JAMA, 293(21), 2601-2608. https://doi.org/10.1001/jama.293.21.2601

Germain, A., Shear, K., Monk, T. H., Houck, P. R., Reynolds, C. F., III., Frank, E., & Buysse, D. J. (2006). Treating complicated grief: Effects on sleep quality. Behavioral Sleep Medicine, 4(3), 152-163. https://doi.org/10.1207/s15402010bsm0403_2

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10864

Shear, M. K., Wang, Y., Skritskaya, N., Duan, N., Mauro, C., & Ghesquiere, A. (2014). Treatment of complicated grief in elderly persons: A randomized clinical trial. JAMA Psychiatry, 71(11), 1287-1295. https://doi.org/10.1001/jamapsychiatry.2014.1242

Glickman, K., Shear, M. K., & Wall, M. (2016). Exploring outcomes related to anxiety and depression in completers of a randomized controlled trial of complicated grief treatment. Clinical Psychology & Psychotherapy, 23(2), 118-124. https://doi.org/10.1002/cpp.1940

Glickman, K., Shear, M. K., & Wall, M. (2017). Mediators of outcome in complicated grief treatment. Journal of Clinical Psychology, 73(7), 817-828. https://doi.org/10.1002/jclp.22384

Glickman, K., Shear, M. K., & Wall, M. (2018). Therapeutic alliance and outcome in complicated grief treatment. International Journal of Cognitive Therapy, 11(2), 222-233. https://doi.org/10.1007/s41811-018-0018-9

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10866

Grote, N. K., Swartz, H. A., Geibel, S. L., Zuckoff, A., Houck, P. R., & Frank, E. (2009). A randomized controlled trial of culturally relevant, brief interpersonal psychotherapy for perinatal depression. Psychiatric Services, 60(3), 313-321. https://doi.org/10.1176/appi.ps.60.3.313

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10867

Grote, N. K., Katon, W. J., Russo, J. E., Lohr, M. J., Curran, M., Galvin, E., & Carson, K. (2015). Collaborative care for perinatal depression in socioeconomically disadvantaged women: A randomized trial. Depression and Anxiety, 32(11), 821-834. https://doi.org/10.1002/da.22405

Grote, N. K., Katon, W. J., Russo, J. E., Lohr, M. J., Curran, M., Galvin, E., & Carson, K. (2016). A randomized trial of collaborative care for perinatal depression in socioeconomically disadvantaged women: The impact of comorbid posttraumatic stress disorder. The Journal of Clinical Psychiatry, 77(11), 1527-1537. https://doi.org/10.4088/JCP.15m10477

Grote, N. K., Simon, G. E., Russo, J., Lohr, M. J., Carson, K., & Katon, W. (2017). Incremental benefit-cost of MOMCare: Collaborative care for perinatal depression among economically disadvantaged women. Psychiatric Services, 68(11), 1164-1171. https://doi.org/10.1176/appi.ps.201600411

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10870

Poleshuck, E. L., Gamble, S. A., Bellenger, K., Lu, N., Tu, X., Sörensen, S., Giles, D. E., & Talbot, N. L. (2014). Randomized controlled trial of Interpersonal Psychotherapy versus enhanced treatment as usual for women with co-occurring depression and pelvic pain. Journal of Psychosomatic Research, 77(4), 264-272. https://doi.org/10.1016/j.jpsychores.2014.07.016

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10872

Rosselló, J., Bernal, G., & Rivera-Medina, C. (2008). Individual and group CBT and IPT for Puerto Rican adolescents with depressive symptoms. Cultural Diversity and Ethnic Minority Psychology, 14(3), 234-245. https://doi.org/10.1037/1099-9809.14.3.234

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10876

Swartz, H. A., Frank, E., Shear, M. K., Thase, M. E., Fleming, M. A., & Scott, J. (2004). A Pilot study of brief interpersonal psychotherapy for depression among women. Psychiatric Services, 55(4), 448-450. https://doi.org/10.1176/appi.ps.55.4.448

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10880

Zlotnick, C., Miller, I. W., Pearlstein, T., Howard, M., Sweeney, P. (2006). A preventive intervention for pregnant women on public assistance at risk for postpartum depression. The American Journal of Psychiatry, 163(8), 1443-1445. https://doi.org/10.1176/appi.ajp.163.8.1443

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10881

Zobel, I., Kech, S., van Calker, D., Dykierek, P., Berger, M., Schneibel, R., & Schramm, E. (2011). Long‐term effect of combined interpersonal psychotherapy and pharmacotherapy in a randomized trial of depressed patients. Acta Psychiatrica Scandinavica, 123(4), 276-282. https://doi.org/10.1111/j.1600-0447.2010.01671.x

Schramm, E., van Calker, D., Dykierek, P., Lieb, K., Kech, S., Zobel, I., Leonhart, R., & Berger, M. (2007). An intensive treatment program of Interpersonal Psychotherapy plus pharmacotherapy for depressed inpatients: Acute and long-term results. American Journal of Psychiatry, 164, 768-777. https://doi.org/10.1176/ajp.2007.164.5.768

This study is ineligible for review because it is not a study of the program or service under review (Study Eligibility Criterion 4.1.6).

Study 10885

Levy, R., Mathai, M., Chatterjee, P., Ongeri, L., Njuguna, S., Onyango, D., Akena, D., Rota, G., Otieno, A., Neylan, T. C., Lukwata, H., Kahn, J. G., Cohen, C. R., Bukusi, D., Aarons, G. A., Burger, R., Blum, K., Nahum-Shani, I., McCulloch, C. E., & Meffert, S. M. (2019). Implementation research for public sector mental health care scale-up (SMART-DAPPER): a sequential multiple, assignment randomized trial (SMART) of non-specialist-delivered psychotherapy and/or medication for major depressive disorder and posttraumatic stress disorder (DAPPER) integrated with outpatient care clinics at a county hospital in Kenya. BMC Psychiatry, 19(1), 424-424. https://doi.org/10.1186/s12888-019-2395-x

This study is ineligible for review because it does not use an eligible study design (Study Eligibility Criterion 4.1.4).